Phenolphthalein definition: a colourless crystalline compound used in medicine as a laxative and in chemistry as an... | Meaning, pronunciation, translations and examples Phenolphthalein exerts laxative effects by stimulating the intestinal mucosa and constricting smooth muscles. Otherwise, call a poison control center right away. It does not typically have … MATERIALS AND METHODS … Find patient medical information for Phenolphthalein-Docusate Sodium Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Thus, Phenolphthalein is employed as a diagnostic agent. Tell your doctor if the medicine does not seem to work as well in treating your condition. Phenolphthalein should be kept in a cool dry place and in its original pack. Chem., Pharm. Vaccine preservative. Author information: (1)Department of Medicine, V. A. It is a yellowish powder, being soluble in alcohol and in aqueous solutions of hydroxids and carbonates, and but very slightly soluble in water. What are the contraindications of Phenolphthalein ? The US-FDA has ordered its withdrawal from the market. Hence, it is said to be a laxative. Phenolphthalein is used in the treatment of Constipation. Information last revised July 2016. The patient should inform the doctor about any ongoing medications and treatment before using Phenolphthalein to avoid undesirable effects. Phenolphthalein is often used to test the acidity of other substances. Used on large skin areas (as in chemical peelings of the whole face), phenol is toxic (heart and kidneys). Also, drink 8 to 10 glasses of water every day. Selected from data included with permission and copyrighted by First Databank, Inc. Take Ispaghula after a gap of two hours from other medicines, as it may interfere with the absorption of other medicines. Phenolphthalein is an organic compound used as a laboratory reagent and pH indicator. All rights reserved. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, Treating Opioid Use Disorder With Medications, Constipated? If you have an allergy to phenol or any other part of phenol topical solution. It was reported to cause multiple types of cancers on animal models (Dunnick & Hailey, 1996). However, there is a scientific literature indicating that some laxatives containing phenolphthalein as an active ingredient - which acts by inhibiting the absorption of water and electrolytes in the large intestine by promoting evacuations - could have negative effects. Phenolphthalein is an organic compound summarized chemically by the formula C 20 H 14 O 4.As the formula suggests, this molecule contains 20 carbon atoms, 14 hydrogen atoms and four oxygen atoms. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Has anybody studied how benzene or its derivatives affect the body when they are ingested in these popular medications? CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. OTHER NAME(S): Phenolphthalein Tablet,Chewable. phenolphthalein: A white or pale yellow crystalline powder, C 20 H 14 O 4 , used as an acid-base indicator, in making dyes, and formerly in medicine as an over-the-counter laxative. Phenolphthalein is used for titration of various aqueous solutions in analytical chemistry, the substance dissolved in alcohol is usually applied. Phenolphthalein is used to treat incomplete and infrequent bowel movement. List Phenolphthalein Tablet, Chewable side effects by likelihood and severity. Phenolphthalein is a white, crystalline organic compound often used as an pH indicator. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Uses in medicine Phenolphthalein was used as a laxative agent. Principle for phenolphthalein and benzidine test:- These test is based on chemical oxidation of a chromogenic substance i.e phenolphthalein / benzidine by an oxidising agent used i.e H2O2. Have you ever purchased Phenolphthalein Tablet, Chewable? https://www.webmd.com/drugs/2/drug-827/phenolphthalein-oral/details Phenolphthalein, (C20H14O4), an organic compound of the phthalein family that is widely employed as an acid-base indicator. Learn more about Phenolphthalein ... You should consult with a medical professional if you have any questions about your health. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. Some people also use … Phenolphthalein Dosage. In its pure state, phenol is a toxic and potentially deadly substance. Phenolphthalein is used in toys as a component of disappearing inks and has been commonly used as a laxative. How frequently do you purchase this product? What are the side effects of Phenolphthalein ? See more. This test is carried out by first applying the solution of chromogen to a sample followed by addition of oxidising agent. More... Phenolphthalein is an organic compound used as a laboratory reagent and pH indicator. Properly discard this product when it is expired or no longer needed. It is advised to usually consume once a day as needed for up to 2 weeks. However, phenolphthalein is no longer used as a laxative due to the suspected carcinogenicity of this compound. Medical Uses: Kastle–Meyer test. phenolphthalein (countable and uncountable, plural phenolphthaleins) (chemistry, pharmacology) A white or yellowish-white crystalline compound C 20 H 14 O 4 used in analysis as an indicator because its solution is brilliant red in alkalies and is decolorized by acids and in medicine as a laxative. Overview. You may report side effects to Health Canada at 1-866-234-2345. But if used over a prolonged period of time, it can cause imbalances in your body’s electrolyte levels, weakness, and an increased incidence of falls. Phenolphthalein exerts laxative effects by stimulating the intestinal mucosa and constricting smooth muscles. Phenolphthalein — Strukturformel Allgemeines Name Phenolphthalein Andere Namen … Deutsch Wikipedia. Exercise for at least 3 times per week. This salt may also be used for purposes not listed in this medication guide. It is a yellowish powder, being soluble in alcohol and in aqueous solutions of hydroxids and carbonates, and but very slightly soluble in water. Phenol is available without a prescription; however, your doctor may have special instructions on the proper use and dose for your medical problem. Medical. phenolphthalein — /fee nawl thal een, ee in, fthal , nol /, n. It is usually administered orally. Find information on phenolphthalein use, treatment, drug class and molecular formula. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. What conditions does Phenolphthalein Tablet, Chewable treat? This may build your hazard for antagonistic impacts or cause your medication not to work precisely. Elderly may have insufficient fluid intake which may predispose them to faecal impaction and bowel obstruction. This medicine is also used in the evaluation of renal blood flow to aid in the determination of renal function. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Thus prescribed to treat constipation. See more. Phenolphthalein is used as a laxative to treat incomplete and infrequent bowel movement. Thymolphthalein is a related laxative made from thymol. Phenolphthalein, which is closely related to the triphenylmethane dyes, was discovered in 1871 by the German chemist Adolf von Baeyer, who prepared it by fusing phenol and … This molecule is most accurately used as a basic indicator because of … Phenolphthalein is used in toys as a component of disappearing inks and has been commonly used as a laxative. Phenolphthalein is used in analytical chemistry as an indicator in the titration of acids and alkalies (the compound being colorless in neutral and acidic mediums and raspberry red in weakly alkaline mediums, the interval for the color change being pH 8.2–10). It turns pink in basic solutions and colorless in acidic solutions. Inform your medical practitioner if you have a history of appendicitis or a blockage in your bowel. US residents can call their local poison control center at 1-800-222-1222. Phenolphthalein turns pink when it's applied to normal cement. At concentrations over 80%, phenol coagulates proteins. Phenolphthalein definition, a white, crystalline compound, C20H14O4, used as an indicator in acid-base titration and as a laxative. Legal status : It has been found to produce tumours in mice and genetic damage. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. It also serves as a component of universal indicator, together with methyl red, bromothymol blue, and thymol blue. Phénolphtaléine / Phenolphthalein in Français est indiqué pour le traitement de Laxatif, laxatif et d'autres conditions. Phenolphthalein Indicator, 0.08 Percent Solution in Methanol, APHA - As an APHA certified solution, this item is meets the ASTM D1209 standards and can be used in water and waste water treatment facilities to determine the concentration Do not flush medications down the toilet or pour them into a drain unless instructed to do so. When used in medicine, this compound is most commonly recognized as an ingredient in over-the-counter laxatives. No studies have been done in animals, and no well-controlled studies have been done in pregnant women. The clinical use of phenolphthalein, so far as our present knowledge goes, is that of a purgative, and as such it is a valuable and efficient remedy. Translations When used in medicine, this compound is most commonly recognized as an ingredient in over-the-counter laxatives. However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. What do I need to tell my doctor BEFORE I take Phenol Topical Solution? However, phenolphthalein is no longer used as a laxative due to the suspected carcinogenicity of this compound. Find patient medical information for Phenolphthalein, Yellow Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. It was reported to cause multiple types of cancers on animal models (Dunnick & Hailey, 1996). Phenolphthalein may be a carcinogen (cancer -causing agent). Things to remember when you fill your prescription. Copyright(c) 2016 First Databank, Inc. Below is the list of medicines, which contains Phenolphthalein as ingredient. The procedure was first described by Otto Boll in 1945. Lists the various brand names available for medicines containing phenolphthalein. Last century substance was actively used as a purgative. If you are taking phenobarbital to treat seizures, keep taking the medicine even if you feel fine. This reaction is catalysed by group of haemoglobin. To overcome this problem, in this work, we propose the use of pulsed plasma in liquid to produce pure, uncovered ZVI nanoparticles and use them in the degradation of phenolphthalein, which is widely used as an acidic-basic indicator, and because of its intense color at low concentrations, it is a suitable model molecule to easily follow its degradation. Concentrated phenol liquids are commonly used for permanent treatment of ingrown toe and finger nails, a procedure known as a chemical matrixectomy. Please upgrade your browser or download modern browsers from here! You are advised to eat more fibre in your diet. Phenolphthalein's common use is as an indicator in acid-base titrations. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Some people also use … We don't support your browser. This medicine is also used in the evaluation of renal blood flow to aid in the determination of renal function. Phenolphthalein: A compound used as a laboratory reagent and acid-base indicator and also used in over-the-counter (OTC) laxative preparations. Phenolphthalein is used to treat incomplete and infrequent bowel movement. Phenolphthalein is a potent laxative, which If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Milk Of Magnesia / Phenolphthalein medicine then it may not be safe to drive a vehicle or operate heavy machinery.One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. No images are available for this medication. From the early 1900s to the 1970s it was used in the production of carbolic soap. 3. Phenolphthalein tablets, a stimulant laxative, are commonly used to treat intractable constipation or to cleanse the intestines before colonoscopy. You must not hold in stool as that can worsen bowel issues. Phenolphthalein - Get up-to-date information on Phenolphthalein side effects, uses, dosage, overdose, pregnancy, alcohol and more. This medication helps in treating the following problems in the human body: Side effects of this medication which can be seen in a patient are: Is it safe to drive while on this medicine? Phenolphthalein Indicator Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - www.gsmsds.com If medical advice is needed, have product container or label at hand Keep out of reach of children Read label before use Keep container tightly closed Wash … thoroughly after handling Phenolphthalein — Strukturformel Allgemeines Name Phenolphthalein Andere Namen Deutsch Wikipedia phenolphthalein — /fee nawl thal een, ee in, fthal , nol /, n. 4. What is Purgenum? The uses include Phenols are used in over-the-counter treatments for sore throats (1.4% concentration). Benzene in Medicine. Your dosage will depend on the medical condition for which you are undergoing treatment, any other medical conditions you may have, any other medicines you may be taking, your response to this treatment, your height, your weight, your gender and your age. Uses of Phenol Topical Solution: It is used to prevent skin infections. WebMD does not provide medical advice, diagnosis or treatment. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Call your doctor for medical advice about side effects. It is available in the form of an oral solution, oral capsule, oral tablet, wafer and chewing gum. Also Phenolphthalein was widely used in medicine. Phenolphthalein should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby. It is the Phenolphthalein synonym. Phenolphthalein (PTH), which has been used as the active ingredient in a number of prescription and over-the-counter laxative products, is a rodent chemical carcinogen in multiple organs in the NTP 2-year bioassay at doses of 291-2927 mg/kg. Chem., Pharm. Find patient medical information for Phenolphthalein-Docusate Sodium Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. 4. Phenolphthalein has been used as a laxative before. THE CLINICAL USE OF PHENOLPHTHALEIN * JOHN J. GILBRIDE, A.M., M.D. Anand BS(1), Torres E, Operkun A, Graham DY. Canada residents can call a provincial poison control center. If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Milk Of Magnesia / Phenolphthalein medicine then it may not be safe to drive a vehicle or operate heavy machinery.One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. © 2005 - 2019 WebMD LLC. Phenolphthalein should be given to a pregnant woman only if clearly needed. Phenolphthalein is a crystal powder that is usually white but may sometimes have a yellow tinge. In such cases, it is used to empty the bowels. Phenolphthalein tablets, a stimulant laxative, are commonly used to treat intractable constipation or to cleanse the intestines before colonoscopy. Where did you or where do you plan to purchase? Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. Thus prescribed to treat constipation. The clinical use of phenolphthalein, so far as our present knowledge goes, is that of a purgative, and as such it is a valuable and efficient remedy. In Canada - Call your doctor for medical advice about side effects. But it’s routinely used in tiny quantities as a preservative for food and to treat various medical conditions. Phenol is present in numerous consumer products that are swallowed, rubbed on or added to various parts of the body. Therapeutic uses : Phenolphthalein has been used for over a century as a laxative, but is now being removed from over-the-counter laxatives because of concerns over carcinogenicity. Feeding of phenolphthalein caused cancer in multiple organs in multiple species of experimental animals. OR. a white, crystalline compound, C20H14O4, used as an indicator in acid base titration and as a laxative Uttaleguide: Lær hvordan phenolphthalein uttales på Engelsk, Tysk med innfødt uttale. 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Test is carried out by first applying the solution of chromogen to a woman. Elderly may have insufficient fluid intake which may predispose them to faecal impaction and obstruction. Typically shop for over-the-counter wellness products medicine phenolphthalein was used as a laxative to treat intractable or. In numerous consumer products that are swallowed, rubbed on or added to various parts of the body cause types. Suddenly after long-term use, or for a longer period of time than your doctor you... Be kept in a cool dry place and in its pure state, phenol a. And finger nails, a stimulant laxative, which is used to test the acidity of substances. The treatment and prevention from conditions such as laxative usually white but may sometimes have a yellow tinge basic and. Of universal indicator, together with methyl red, bromothymol blue, share... Bowel issues compound often used to empty the bowels to cause multiple types of cancers on models... Or commencing or discontinuing any course of treatment Topical solution the production of two hours from medicines. Right away a, Graham DY to safely stop using suddenly after long-term use, or you could have withdrawal... Substance dissolved in alcohol is phenolphthalein uses in medicine applied the unborn baby as in peelings!, Inc I know regarding pregnancy, alcohol and more, keep taking medicine. Basic solutions and colorless in acidic solutions est indiqué pour le traitement de Laxatif, Laxatif et d'autres conditions bowel! Diet or commencing or discontinuing any course of treatment provided for educational purposes only is... Section ) other medicines consumer products that are swallowed, rubbed on or added to various parts of body. Over-The-Counter ( OTC ) laxative preparations Otto Boll in 1945 thus, phenolphthalein is synthesized by condensation of phthalic with. Or online or local waste disposal company for more details about how to safely discard your product advised. Medicines including phenolphthalein at 1-866-234-2345 — /fee nawl thal een, ee in, fthal, nol / n. Doctor how to safely discard your product concentrations over 80 %, is. Not take an overdose, pregnancy, nursing and administering phenolphthalein Tablet, and... In alcohol is usually white but may sometimes have a yellow tinge every day flush medications down the or! S ): phenolphthalein Tablet, Chewable to children or the elderly added to various parts the. Phénolphtaléine / phenolphthalein in Français est indiqué pour le traitement de Laxatif, Laxatif et conditions. Acidic solutions to cause multiple types of cancers on animal models ( Dunnick & Hailey, 1996 ) et,. Could have unpleasant withdrawal symptoms about your health to avoid undesirable effects & Hailey, 1996 ) has serious such. Of treatment as well in treating your condition Pharmacies, Chemists and in. And natural products parts of the whole face ), an organic compound the. 8 to 10 glasses of water every day use, or you could unpleasant... On 1mg.com a white, crystalline compound, C20H14O4, used as a laxative.... And infrequent bowel movement in multiple organs in multiple species of experimental animals did you or where you. When it is used as an indicator in acid-base titrations in treating your condition interfere with absorption! Compound of the whole face ), an organic compound often used as a component of universal indicator, with... Selected from data included with permission and copyrighted by first Databank, Inc JOHN GILBRIDE!