EPC core team members must disclose any financial conflicts of interest greater than $1,000 and any other relevant business or professional conflicts of interest. Specific study methodology or conduct will be used to judge potential risk of bias with respect to each domain following guidance in the Cochrane Handbook for Systematic Reviews of Interventions, Version 5.1.0.7. The first step in cultural competency is an exposure to cultures other than one’s own. Systematic reviews must include risk of bias assessment with validated tools. Are confounding and/or effect modifying variables assessed using valid and reliable measures across all study participants? The EPC considers all peer review comments on the draft report in preparation of the final report. The preliminary risk of bias assessment form is provided in Appendix B. Similarly, linguistic competence means something different to a provider treating a person for whom English is a second language than to a provider treating a transgendered person. Provider training and motivation outcomes, such as post-test competencies, knowledge, changes in attitudes, Provider beliefs/cognitions about the priority population, such as reducing stereotyping and stigmatization, Improved specific knowledge of health needs unique to LGBTQI community, Provider behavior, such as clinical decision-making, communication, Patient learning/knowledge, including linguistic competence regarding gender-diversity, Patient experience and satisfaction, such as improved perceptions of care, Patient health behaviors, such as tobacco use or health seeking behaviors, Improved mental health outcomes, such as depression, anxiety, suicidality, peer/familial/intimate relationships, substance use, Improved medical health outcomes, such as reduction in obesity, improved sexual health, Adverse events; unintended negative consequences of intervention, Provider training and motivation outcomes, such as post-test competencies, knowledge, changes in attitudes, willingness to serve and perceived competence in service people with disabilities, Provider beliefs/cognitions the priority population, such as reducing stereotyping and stigmatization, Improved mental health outcomes, such as depression, substance use, Improved medical health outcomes, such as reduction in obesity, metabolic disorders, heart disease, breast cancer, Use of preventive services, and other access to care measures, Patient beliefs/attitudes such as improved trust, perceived racism, Improved medical health outcomes, such as reduction in obesity, kidney disease, heart disease, breast cancer, sickle cell disease, Cultural competence/ culturally appropriate care provider education and training, Cultural competence/ culturally appropriate care clinic-based interventions targeted to patients, Cultural competence/ culturally appropriate care clinic-based interventions targeted to providers, Head-to-head trials of different strategies, Provider training and motivation outcomes (competencies, knowledge, changes in attitudes), Provider beliefs/cognitions about the priority population, reducing stereotyping, stigmatization, Provider improved specific knowledge of health needs unique to LGBT community, Use of preventive services and other access to care measures, Patient mental health care outcomes (depression, anxiety, suicidality, substance use, peer/familial/ intimate relationships), Unintended negative consequences of intervention, Patient mental health care outcomes (depression, substance use), Provider knowledge, attitudes, and competencies (skills) in providing culturally competent health care, Patient beliefs/cognitions such as improved trust, perceived racism, Availability of culturally competent health care across population groups, Studies of any of the priority populations; LGBTQI, disability, race/ethnic groups. 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